Régime MIND et alzheimer

Abstract

Background

In a previous study, higher concordance to the MIND diet, a hybrid Mediterranean-Dietary Approaches to Stop Hypertension diet, was associated with slower cognitive decline. In this study we related these three dietary patterns to incident Alzheimer's disease (AD).

Methods

We investigated the diet-AD relations in a prospective study of 923 participants, ages 58 to 98 years, followed on average 4.5 years. Diet was assessed by a semiquantitative food frequency questionnaire.

Results

In adjusted proportional hazards models, the second (hazards ratio or HR = 0.65, 95% confidence interval or CI 0.44, 0.98) and highest tertiles (HR = 0.47, 95% CI 0.26, 0.76) of MIND diet scores had lower rates of AD versus tertile 1, whereas only the third tertiles of the DASH (HR = 0.61, 95% CI 0.38, 0.97) and Mediterranean (HR = 0.46, 95% CI 0.26, 0.79) diets were associated with lower AD rates.

Conclusion

High adherence to all three diets may reduce AD risk. Moderate adherence to the MIND diet may also decrease AD risk.


Le régime MIND?
Dans le régime MIND, il faut privilégier les aliments de dix groupes protecteurs pour le cerveau (légumes à feuilles vertes, autres légumes, noix, baies, haricots, céréales complètes, poissons, volailles, huile d’olive et vin) et limiter ses apports en aliments provenant de cinq autres groupes jugés « peu sains » : viandes rouges, pâtisseries et sucreries, beurre ou margarine, fromage, fast food ou aliments frits.